Oral Fluid Drug Testing

• Can substances such as food, beverages, over-the-counter medication, and mouthwash affect the oral fluid drug test results?

  Yes. For this reason, the donor is to refrain from consumption of food or beverages for 10 minutes prior to specimen collection.¹

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• How does the drug detection window for oral fluid compare to urine and hair?

  Drug detection times vary depending on the dose, sensitivity of the testing method used, preparation and route of administration, duration of use (acute or chronic), the matrix that is analyzed, the molecule or metabolite that is looked for, the pH and concentration of the matrix (urine, oral fluid), and variations in metabolic and renal clearance. In general, the detection time is longest in hair, followed by urine and oral fluid. Drugs in hair may be detectable for up to 90 days, whereas drugs in urine are generally detectable for one to seven days (or longer in chronic users) and in oral fluid from five to 48 hours.²

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• What is the drug detection window for oral fluid testing?

  Depending on the drug used, dose, and route of administration, a drug may be detected in oral fluid in less than one hour and remain detectable for five up to 48 hours after last use.^1,2

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• Why is the oral fluid specimen placed in a fluid buffer?

  The buffer solution is used to inhibit bacterial growth.

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