Acute Measles Panel, IgM Antibody and PCR

A negative test does not rule out infection with measles virus. Results should be interpreted in conjunction with clinical finding.

The absence of IgM-class antibodies suggests lack of an acute phase infection with measles virus. However, serology may be negative for IgM-class antibodies in early disease, and results should be interpreted in the context of clinical findings.

Testing for IgM-class antibodies to measles should be limited to patients with clinically compatible disease. Specimens should be collected as soon as possible after the development of rash to maximize the sensitivity of measles RNA detection.

Improperly collected samples may result in false negative results.

PCR assays may be impacted by viral variants and may result in reduced sensitivity or false negative results.

The Measles PCR was developed and its performance characteristics determined by Labcorp. It has not been been cleared or approved by the Food and Drug Administration. been cleared or approved by the Food and Drug Administration.

A negative test does not rule out infection with measles virus. Results should be interpreted in conjunction with clinical finding.

The absence of IgM-class antibodies suggests lack of an acute phase infection with measles virus. However, serology may be negative for IgM-class antibodies in early disease, and results should be interpreted in the context of clinical findings.

Testing for IgM-class antibodies to measles should be limited to patients with clinically compatible disease. Specimens should be collected as soon as possible after the development of rash to maximize the sensitivity of measles RNA detection.

Improperly collected samples may result in false negative results.

PCR assays may be impacted by viral variants and may result in reduced sensitivity or false negative results.

The Measles PCR was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administratio been cleared or approved by the Food and Drug Administration.

Clinical Overview of Measels. Centers for Disease Control and Prevention website: https://www.cdc.gov/measles/hcp/clinical-overview/index.html#cdc_clinical_overview_test_dia-diagnosis-and-laboratory-testing. Updated July 15, 2024. Accessed October 2024.

Clinical Overview of Measles. Centers for Disease Control and Prevention website: https://www.cdc.gov/measles/hcp/clinical-overview/index.html#cdc_clinical_overview_test_dia-diagnosis-and-laboratory-testing. Updated July 15, 2024. Accessed October 2024.