Allergen Profile, Pediatric, IgE With Component Reflexes

TEST: 608035
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CPT: 82785; 86003(x24); 86008
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Test Includes

Alternaria alternata; Brazil nut; Candida albicans; cashew nut; cat dander; cedar; codfish; cockroach, German; Dermatophagoides pteronyssinus; dog dander; egg white; hazelnut (filbert); immunoglobulin E, total; milk; mouse urine; peanut (whole); salmon; scallop; sesame seed; shrimp; soybean; timothy grass; tuna; walnut; wheat; w5-gliadin (tri-19)

• If milk IgE ≥ 0.35 kU/L, reflex tests α-lactalbumin, β-lactoglobulin and casein will be added.

• If egg white IgE ≥ 0.35 kU/L, reflex tests ovalbumin and ovomucoid will be added.

• If sesame IgE ≥ 0.10 kU/L, reflex test Ses I 1 will be added.

• If walnut IgE ≥ 0.10 kU/L, reflex tests Jug r 1 and Jug r 3 will be added.

• If hazelnut (filbert) IgE ≥0.10 kU/L, reflex tests Cor a 1, Cor a 8, Cor a 9 and Cor a 14 will be added.

• If cashew nut IgE ≥ 0.10 kU/L, reflex test Ana o 3 will be added.

• If Brazil nut IgE ≥ 0.10 kU/L, reflex test Ber e 1 will be added.

• If peanut (whole) IgE ≥ 0.10 kU/L, reflex tests Ara h 1, Ara h 2, Ara h 3, Ara h 6, Ara h 8 and Ara h 9 will be added.

• If wheat IgE ≥ 0.10 kU/L, one or more of the following components may be tested: Gliadin, Tri a 14 (wheat nsLTP), Phl p 12 (Timothy grass profilin) and/or Cross-reactive Carbohydrate Determinant (CCD).

• If cat dander IgE ≥0.35 kU/L, reflex tests Fel d 1 IgE, Fel d 2 IgE and Fel d 4 IgE will be added.

• If dog dander IgE ≥0.35 kU/L, reflex tests Can f 1 IgE, Can f 2 IgE, Can f 3 IgE and Can f 5 IgE will be added.

Expected Turnaround Time

3 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Related Documents

For more information, please view the literature below.

Food Allergy Testing Brochure

Specimen Requirements

Specimen

Serum

Volume

4 mL

Minimum Volume

3 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube or gel-barrier tube

Collection

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage Instructions

Room temperature

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

3 months

Freeze/thaw cycles

Stable x3

Test Details

Use

This panel is designed to measure the extent of allergen sensitization in children and adolescents.

Methodology

Thermo Fisher ImmunoCAP® Allergen-specific IgE

References

Belgrave DC, Granell R, Simpson A, et al. Developmental profiles of eczema, wheeze, and rhinitis: two population-based birth cohort studies. PLoS Med. 2014 Oct 21;11(10):e1001748.25335105
Casale TB, Pedersen S, Del Rio PR, Liu AH, Demoly P, Price D. The Role of Aeroallergen Sensitization Testing in Asthma Management. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2526-2532.32687905
Chang TS, Lemanske RF Jr, Guilbert TW, et al. Evaluation of the modified asthma predictive index in high-risk preschool children. J Allergy Clin Immunol Pract. 2013 Mar;1(2):152-156.24187656
Fabiano Filho RC, Geller RJ, Santos LC, et al. Performance of Three Asthma Predictive Tools in a Cohort of Infants Hospitalized With Severe Bronchiolitis. Front Allergy. 2021 Oct 22;2:758719.35387011
Guilbert TW, Morgan WJ, Zeiger RS, et al. Atopic characteristics of children with recurrent wheezing at high risk for the development of childhood asthma. J Allergy Clin Immunol. 2004 Dec;114(6):1282-1287.15577824
Gupta RS, Warren CM, Smith BM, et al. The Public Health Impact of Parent-Reported Childhood Food Allergies in the United States. Pediatrics. 2018 Dec;142(6):e20181235.30455345
Savage J, Sicherer S, Wood R. The Natural History of Food Allergy. J Allergy Clin Immunol Pract. 2016 Mar-Apr;4(2):196-203; quiz 204.26968958
Sicherer SH, Sampson HA. Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. J Allergy Clin Immunol. 2018 Jan;141(1):41-58.29157945
Sicherer SH, Sampson HA. Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. J Allergy Clin Immunol. 2014 Feb;133(2):291-307; quiz 308.24388012
Sicherer SH, Warren CM, Dant C, Gupta RS, Nadeau KC. Food Allergy from Infancy Through Adulthood. J Allergy Clin Immunol Pract. 2020 Jun;8(6):1854-1864.32499034

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
608035 Allergen Profile, Pediatric 602444 Class Description N/A
608035 Allergen Profile, Pediatric 002173 Immunoglobulin E, Total IU/mL 19113-0
608035 Allergen Profile, Pediatric 602457 F014-IgE Soybean kU/L 6248-9
608035 Allergen Profile, Pediatric 602465 F003-IgE Codfish kU/L 6082-2
608035 Allergen Profile, Pediatric 602510 F040-IgE Tuna kU/L 6270-3
608035 Allergen Profile, Pediatric 602507 F041-IgE Salmon kU/L 6237-2
608035 Allergen Profile, Pediatric 602478 F338-IgE Scallop kU/L 7691-9
608035 Allergen Profile, Pediatric 602473 F024-IgE Shrimp kU/L 6246-3
608035 Allergen Profile, Pediatric 602689 E072-IgE Mouse Urine kU/L 6181-2
608035 Allergen Profile, Pediatric 602488 I006-IgE Cockroach, German kU/L 6078-0
608035 Allergen Profile, Pediatric 602506 G006-IgE Timothy Grass kU/L 6265-3
608035 Allergen Profile, Pediatric 602491 T006-IgE Cedar, Mountain kU/L 6178-8
608035 Allergen Profile, Pediatric 602455 M006-IgE Alternaria alternata kU/L 6020-2
608035 Allergen Profile, Pediatric 602548 M005-IgE Candida albicans kU/L 6059-0
608035 Allergen Profile, Pediatric 602467 D001-IgE D pteronyssinus kU/L 6096-2
608035 Allergen Profile, Pediatric 606844 F002-IgE Milk kU/L 7258-7
608035 Allergen Profile, Pediatric 606841 F001-IgE Egg White kU/L 6106-9
608035 Allergen Profile, Pediatric 607741 F010-IgE Sesame Seed kU/L 6242-2
608035 Allergen Profile, Pediatric 606842 F017-IgE Hazelnut (Filbert) kU/L 6136-6
608035 Allergen Profile, Pediatric 606845 F256-IgE Walnut kU/L 6273-7
608035 Allergen Profile, Pediatric 606837 F202-IgE Cashew Nut kU/L 6718-1
608035 Allergen Profile, Pediatric 606836 F018-IgE Brazil Nut kU/L 6050-9
608035 Allergen Profile, Pediatric 606414 F013-IgE Peanut kU/L 6206-7
608035 Allergen Profile, Pediatric 606838 E001-IgE Cat Dander kU/L 6833-8
608035 Allergen Profile, Pediatric 606840 E005-IgE Dog Dander kU/L 6098-8
608035 Allergen Profile, Pediatric 607843 F416-IgE Tri a 19(w-5 gliadin) kU/L 58752-7
608035 Allergen Profile, Pediatric 607841 F004-IgE Wheat kU/L 6276-0
608035 Allergen Profile, Pediatric 607999 Reflex N/A
Reflex Table for F002-IgE Milk
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603848 Panel 603848 602731 F076-IgE Alpha Lactalbumin kU/L 7445-0
Reflex Table for F002-IgE Milk
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603848 Panel 603848 602505 F077-IgE Beta Lactoglobulin kU/L 41397-1
Reflex Table for F002-IgE Milk
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603848 Panel 603848 602554 F078-IgE Casein kU/L 6062-4
Reflex Table for F001-IgE Egg White
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603851 Panel 603851 602791 F232-IgE Ovalbumin kU/L 7556-4
Reflex Table for F001-IgE Egg White
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 603851 Panel 603851 602792 F233-IgE Ovomucoid kU/L 7557-2
Reflex Table for F010-IgE Sesame Seed
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607742 F449-IgE Ses i 1 607742 F449-IgE Ses i 1 kU/L Pending
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604735 F428-IgE Cor a 1 kU/L 69421-6
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604741 F425-IgE Cor a 8 kU/L 58753-5
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604742 F440-IgE Cor a 9 kU/L 65765-0
Reflex Table for F017-IgE Hazelnut (Filbert)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604726 Panel 604726 604743 F439-IgE Cor a 14 kU/L 81788-2
Reflex Table for F256-IgE Walnut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604721 Panel 604721 604719 F441-IgE Jug r 1 kU/L 81790-8
Reflex Table for F256-IgE Walnut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604721 Panel 604721 604720 F442-IgE Jug r 3 kU/L 81789-0
Reflex Table for F202-IgE Cashew Nut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604239 Panel 604239 604161 F443-IgE Ana o 3 kU/L 82539-8
Reflex Table for F018-IgE Brazil Nut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604350 Panel 604350 604158 F354-IgE Ber e 1 kU/L 64963-2
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603835 F422-IgE Ara h 1 kU/L 58779-0
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603836 F423-IgE Ara h 2 kU/L 58778-2
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603838 F424-IgE Ara h 3 kU/L 58777-4
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 605970 F447-IgE Ara h 6 kU/L 90880-6
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603839 F352-IgE Ara h 8 kU/L 63477-4
Reflex Table for F013-IgE Peanut
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 604845 Panel 604845 603840 F427-IgE Ara h 9 kU/L 64965-7
Reflex Table for E001-IgE Cat Dander
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 606578 Panel 606578 606587 E094-IgE Fel d 1 kU/L 78384-5
Reflex Table for E001-IgE Cat Dander
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 606578 Panel 606578 606645 E220-IgE Fel d 2 kU/L 19732-7
Reflex Table for E001-IgE Cat Dander
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 606578 Panel 606578 606647 E228-IgE Fel d 4 kU/L 64976-4
Reflex Table for E005-IgE Dog Dander
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 606648 Panel 606648 606649 E101-IgE Can f 1 kU/L 58773-3
Reflex Table for E005-IgE Dog Dander
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 606648 Panel 606648 606651 E102-IgE Can f 2 kU/L 58772-5
Reflex Table for E005-IgE Dog Dander
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 606648 Panel 606648 606653 E221-IgE Can f 3 kU/L 19738-4
Reflex Table for E005-IgE Dog Dander
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 606648 Panel 606648 606655 E226-IgE Can f 5 kU/L 64973-1
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607842 F098-IgE Gliadin, Wheat kU/L 82583-6
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607844 F433-IgE Tri a 14 (nsLTP) kU/L 64966-5
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607845 G212-IgE Phl p 12 (Profilin) kU/L 34428-3
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607959 O214-IgE CCD Determinants 602444 Class Description N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607959 O214-IgE CCD Determinants 606381 O214-IgE CCD Determinants kU/L 58984-6
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607959 O214-IgE CCD Determinants 606381 O214-IgE CCD Determinants kU/L 58984-6
Reflex 5 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607957 G212-IgE Phl p 12 (Profilin) 607958 Reflex N/A
Reflex 4 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607954 F433-IgE Tri a 14 (nsLTP) 607951 Reflex N/A
Reflex 3 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607953 F098-IgE Gliadin, Wheat 607956 Reflex N/A
Reflex 2 607851 Reflex to Litholink 607851 Reflex to Litholink N/A
Reflex Table for Reflex
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 607851 Reflex to Litholink 607851 Reflex to Litholink N/A

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