Autoimmune Myelopathy Profile

TEST: 505592
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CPT: 84182; 86051; 86255(x15); 86341; 86362
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Expected Turnaround Time

5 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

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Specimen Requirements

Specimen

Serum (gel barrier tube or red-top tube)

Volume

2 mL

Minimum Volume

1 mL

Container

Gel barrier tube, serum transfer tube

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gross hemolysis; grossly lipemic; gross icetrus

Test Details

Use

This test can assist in the diagnosis (paraneoplastic or idiopathic autoimmune) and aid distinction from other causes of myelopathy (sarcoidosis, vascular disease, multiple sclerosis). Early testing may assist in early diagnosis of occult cancer, prompt initiation of immune therapies, or both.

Limitations

This test was developed and its performance characteristics determined by Labcorp in accordance with CLIA requirements. This test has not been cleared or approved by the Food and Drug Administration.

Methodology

Immunofluorescence, EIA, Immunoblot

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
505592 Autoimmune Myelopathy Ab 505548 Interpretation 56850-1
505592 Autoimmune Myelopathy Ab 505241 Anti-Hu Ab 49738-8
505592 Autoimmune Myelopathy Ab 505243 Anti-Ri Ab 43187-4
505592 Autoimmune Myelopathy Ab 505469 Antineuronal nuclear Ab Type 3 43102-3
505592 Autoimmune Myelopathy Ab 505245 PCA Type-1 (Anti-Yo) Ab 84924-0
505592 Autoimmune Myelopathy Ab 505471 Purkinje Cell Cyto Ab Type 2 84925-7
505592 Autoimmune Myelopathy Ab 505472 Purkinje Cell Cyto Ab Type Tr 84926-5
505592 Autoimmune Myelopathy Ab 505470 Amphiphysin Antibody 33422-7
505592 Autoimmune Myelopathy Ab 505486 CRMP-5 IgG 43103-1
505592 Autoimmune Myelopathy Ab 505487 CRMP-5 IgG Line Blot 47401-5
505592 Autoimmune Myelopathy Ab 505488 AGNA-1 84927-3
505592 Autoimmune Myelopathy Ab 505491 DPPX Antibody 82976-2
505592 Autoimmune Myelopathy Ab 505492 mGluR1 Antibody 94347-2
505592 Autoimmune Myelopathy Ab 505519 AMPA-R1 Antibody 84929-9
505592 Autoimmune Myelopathy Ab 505524 AMPA-R2 Antibody 84930-7
505592 Autoimmune Myelopathy Ab 505534 GABA-B-R Antibody 84931-5
505592 Autoimmune Myelopathy Ab 505536 NMDA-R Antibody 84928-1
505592 Autoimmune Myelopathy Ab 505537 GAD65 Antibody 94345-6
505592 Autoimmune Myelopathy Ab 505547 Aquaporin 4 Antibody 61430-5
505592 Autoimmune Myelopathy Ab 505311 MOG Antibody, Cell-based IFA 91545-4
Reflex Table for Anti-Hu Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505242 Anti-Hu Ab Line Blot 505242 Anti-Hu Ab Line Blot 94389-4
Reflex Table for Anti-Ri Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505244 Anti-Ri Ab Line Blot 505244 Anti-Ri Ab Line Blot 94387-8
Reflex Table for PCA Type-1 (Anti-Yo) Ab
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505246 Anti-Yo Ab Line Blot 505246 Anti-Yo Ab Line Blot 94271-4
Reflex Table for Purkinje Cell Cyto Ab Type Tr
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505473 PCA-Tr Line Blot 505473 PCA-Tr Line Blot 88734-9
Reflex Table for Amphiphysin Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505474 Amphiphysin Line Blot 505474 Amphiphysin Line Blot 94385-2
Reflex Table for CRMP-5 IgG
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505487 CRMP-5 IgG Line Blot 505487 CRMP-5 IgG Line Blot 47401-5
Reflex Table for AGNA-1
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505489 AGNA-1 Line Blot 505489 AGNA-1 Line Blot 82444-1
Reflex Table for DPPX Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505281 DPPX Cell-based IFA 505281 DPPX Cell-based IFA 94676-4
Reflex 2 505282 DPPX Antibody, Titer, Serum 505282 DPPX Antibody, Titer, Serum 94675-6
Reflex Table for mGluR1 Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505493 mGluR1 Cell-based IFA 505493 mGluR1 Cell-based IFA 93498-4
Reflex 2 505494 mGluR1 IF Titer 505494 mGluR1 IF Titer 93499-2
Reflex Table for AMPA-R1 Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505521 AMPA-R-1 Cell-based IFA 505521 AMPA-R-1 Cell-based IFA 93869-6
Reflex 2 505523 AMPA-R-1 IF Titer 505523 AMPA-R-1 IF Titer 95604-5
Reflex Table for AMPA-R2 Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505532 AMPA-R-2 Cell-based IFA 505532 AMPA-R-2 Cell-based IFA 93868-8
Reflex 2 505533 AMPA-R-2 IF Titer 505533 AMPA-R-2 IF Titer 95603-7
Reflex Table for GABA-B-R Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505267 GABA-B Receptor Cell-based IFA 505267 GABA-B Receptor Cell-based IFA 93867-0
Reflex 2 505268 GABA-B Receptor Antibody Titer 505268 GABA-B Receptor Antibody Titer 95602-9
Reflex Table for NMDA-R Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505376 NMDAR Antibody, Cell-based IFA 505376 NMDAR Antibody, Cell-based IFA 90839-2
Reflex 2 505377 Anti-NMDAR Antibody Titer 505377 Anti-NMDAR Antibody Titer 90840-0
Reflex Table for GAD65 Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505546 GAD65 Line Blot 505546 GAD65 Line Blot 81725-4
Reflex Table for Aquaporin 4 Antibody
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 004213 NMO IgG Autoantibodies 004213 NMO IgG Autoantibodies U/mL 68548-7
Reflex Table for MOG Antibody, Cell-based IFA
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 505312 Anti-MOG Antibody Titer, Serum 505312 Anti-MOG Antibody Titer, Serum 91544-7

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf