Multiple Sclerosis Monitoring Profile

TEST: 484495
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CPT: 83520(x2)
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Test Includes

Glial Fibrillary Acid Protein, Serum; GFAP, Serum Z Score; Neurofilament Light Chain, Serum; NFL, Serum Z Score

Expected Turnaround Time

1 - 3 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements

Specimen

Serum

Volume

2 mL

Minimum Volume

1 mL (Note: This volume does not allow for repeat testing.)

Container

Gel-barrier tube (preferred) or red-top tube

Collection

If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage Instructions

Room temperature

Stability Requirements

TemperaturePeriod
Room temperature14 days
Refrigerated14 days
Frozen14 days
Freeze/thaw cycleStable x3

Test Details

Use

This test is used to monitor Neurofilament Light Chain, Serum (NfL) and Glial Fibrillary Acid Protein, Serum (GFAP) values in multiple sclerosis patients.

Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

Methodology

Roche Diagnostics Electrochemiluminescence Immunoassay (ECLIA)

For Providers

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf