Lacosamide

TEST: 007012
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CPT: 80235
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Synonyms

  • Vimpat®

Expected Turnaround Time

3 - 4 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

Specimen Requirements

Specimen

Serum or plasma

Volume

0.25 mL

Minimum Volume

0.10 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection

Transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

105 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gel-barrier tube

Test Details

Use

Lacosamide is a functional amino acid specifically synthesized as an anticonvulsant drug. In addition to being approved for use as adjunctive therapy in the treatment of partial-onset seizures, it is being investigated as a treatment for diabetic neuropathic pain.

Limitations

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

References

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: A summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan; 83(1)1-43. 19008076
Krasowski M. Therapeutic drug monitoring of the newer anti-epilepsy medications. Pharmaceuticals (Basel). 2010 Jun 11; 3(6):1909-1935. 20640233

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
007012 Lacosamide 59297-2 007016 Lacosamide ug/mL 59297-2

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