Autoimmune Epilepsy Evaluation Profile

Test Number 505490

Test number copied

CPT 86255(x21); 86341

Synonyms

Autoimmune Epilepsy Panel
Paraneoplastic

Test Details

Methodology

Immunofluorescence, EIA, Immunoblot

Result Turnaround Time

5 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Use

For the detection of antineuronal autoantibodies that help in the diagnosis of paraneoplastic syndromes and autoimmune encephalopathies and related conditions

Limitations

This test was developed and its performance characteristics determined by Labcorp in accordance with CLIA requirements. This test has not been cleared or approved by the Food and Drug Administration.

Custom Additional Information

This test should be considered for the differential evaluation of seizures of unknown origin that happen several times a day right from the beginning, focal seizures, and facial brachial dystonic seizures. For adults and patients with suspicion of cancer, additional evaluation of paraneoplastic autoantibodies is recommended; refer to Autoimmune Neurology/Paraneoplastic Profile [505500].

Specimen Requirements

Specimen

Serum (gel barrier tube or red-top tube)

Volume

2 mL

Minimum Volume

1 mL (Note: This volume does not allow for repeat testing.)

Container

Gel barrier tube, serum transfer tube

Stability Requirements

Temperature	Period
Room temperature	14 days
Refrigerated	14 days
Frozen	14 days
Freeze/thaw cycles	Stable x3

Causes for Rejection

Gross hemolysis; grossly lipemic; gross icetrus

LOINC® Map

Order Code	Order Code Name	Result Code	Result Code Name	Result LOINC
505490	Autoimmune Epilepsy Ab	505548	Interpretation	56850-1
505490	Autoimmune Epilepsy Ab	505241	Anti-Hu Ab	49738-8
505490	Autoimmune Epilepsy Ab	505243	Anti-Ri Ab	43187-4
505490	Autoimmune Epilepsy Ab	505469	Antineuronal nuclear Ab Type 3	43102-3
505490	Autoimmune Epilepsy Ab	505245	PCA Type-1 (Anti-Yo) Ab	84924-0
505490	Autoimmune Epilepsy Ab	505471	Purkinje Cell Cyto Ab Type 2	84925-7
505490	Autoimmune Epilepsy Ab	505472	Purkinje Cell Cyto Ab Type Tr	84926-5
505490	Autoimmune Epilepsy Ab	505470	Amphiphysin Antibody	33422-7
505490	Autoimmune Epilepsy Ab	505486	CRMP-5 IgG	43103-1
505490	Autoimmune Epilepsy Ab	505488	AGNA-1	84927-3
505490	Autoimmune Epilepsy Ab	505491	DPPX Antibody	82976-2
505490	Autoimmune Epilepsy Ab	505492	mGluR1 Antibody	94347-2
505490	Autoimmune Epilepsy Ab	505497	IgLON5 Antibody	96476-7
505490	Autoimmune Epilepsy Ab	505502	Ma2/Ta Antibody	35458-9
505490	Autoimmune Epilepsy Ab	505511	Zic4 Antibody	38915-5
505490	Autoimmune Epilepsy Ab	505513	DNER Antibody	84926-5
505490	Autoimmune Epilepsy Ab	505519	AMPA-R1 Antibody	84929-9
505490	Autoimmune Epilepsy Ab	505524	AMPA-R2 Antibody	84930-7
505490	Autoimmune Epilepsy Ab	505534	GABA-B-R Antibody	84931-5
505490	Autoimmune Epilepsy Ab	505536	NMDA-R Antibody	84928-1
505490	Autoimmune Epilepsy Ab	505537	GAD65 Antibody	94345-6
505490	Autoimmune Epilepsy Ab	505431	CASPR2 Antibody,Cell-based IFA	82979-6
505490	Autoimmune Epilepsy Ab	505356	LGI1 Antibody, Cell-based IFA	82978-8
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505548
Result Code Name	Interpretation
UofM
Result LOINC	56850-1
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505241
Result Code Name	Anti-Hu Ab
UofM
Result LOINC	49738-8
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505243
Result Code Name	Anti-Ri Ab
UofM
Result LOINC	43187-4
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505469
Result Code Name	Antineuronal nuclear Ab Type 3
UofM
Result LOINC	43102-3
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505245
Result Code Name	PCA Type-1 (Anti-Yo) Ab
UofM
Result LOINC	84924-0
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505471
Result Code Name	Purkinje Cell Cyto Ab Type 2
UofM
Result LOINC	84925-7
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505472
Result Code Name	Purkinje Cell Cyto Ab Type Tr
UofM
Result LOINC	84926-5
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505470
Result Code Name	Amphiphysin Antibody
UofM
Result LOINC	33422-7
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505486
Result Code Name	CRMP-5 IgG
UofM
Result LOINC	43103-1
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505488
Result Code Name	AGNA-1
UofM
Result LOINC	84927-3
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505491
Result Code Name	DPPX Antibody
UofM
Result LOINC	82976-2
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505492
Result Code Name	mGluR1 Antibody
UofM
Result LOINC	94347-2
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505497
Result Code Name	IgLON5 Antibody
UofM
Result LOINC	96476-7
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505502
Result Code Name	Ma2/Ta Antibody
UofM
Result LOINC	35458-9
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505511
Result Code Name	Zic4 Antibody
UofM
Result LOINC	38915-5
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505513
Result Code Name	DNER Antibody
UofM
Result LOINC	84926-5
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505519
Result Code Name	AMPA-R1 Antibody
UofM
Result LOINC	84929-9
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505524
Result Code Name	AMPA-R2 Antibody
UofM
Result LOINC	84930-7
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505534
Result Code Name	GABA-B-R Antibody
UofM
Result LOINC	84931-5
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505536
Result Code Name	NMDA-R Antibody
UofM
Result LOINC	84928-1
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505537
Result Code Name	GAD65 Antibody
UofM
Result LOINC	94345-6
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505431
Result Code Name	CASPR2 Antibody,Cell-based IFA
UofM
Result LOINC	82979-6
Order Code	505490
Order Code Name	Autoimmune Epilepsy Ab
Order Loinc
Result Code	505356
Result Code Name	LGI1 Antibody, Cell-based IFA
UofM
Result LOINC	82978-8

Reflex Table for Anti-Hu Ab
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505242	Anti-Hu Ab Line Blot	505242	Anti-Hu Ab Line Blot	94389-4
Reflex 1
Order Code	505242
Order Name	Anti-Hu Ab Line Blot
Result Code	505242
Result Name	Anti-Hu Ab Line Blot
UofM
Result LOINC	94389-4

Reflex Table for Anti-Ri Ab
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505244	Anti-Ri Ab Line Blot	505244	Anti-Ri Ab Line Blot	94387-8
Reflex 1
Order Code	505244
Order Name	Anti-Ri Ab Line Blot
Result Code	505244
Result Name	Anti-Ri Ab Line Blot
UofM
Result LOINC	94387-8

Reflex Table for PCA Type-1 (Anti-Yo) Ab
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505246	Anti-Yo Ab Line Blot	505246	Anti-Yo Ab Line Blot	94271-4
Reflex 1
Order Code	505246
Order Name	Anti-Yo Ab Line Blot
Result Code	505246
Result Name	Anti-Yo Ab Line Blot
UofM
Result LOINC	94271-4

Reflex Table for Purkinje Cell Cyto Ab Type Tr
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505473	PCA-Tr Line Blot	505473	PCA-Tr Line Blot	88734-9
Reflex 1
Order Code	505473
Order Name	PCA-Tr Line Blot
Result Code	505473
Result Name	PCA-Tr Line Blot
UofM
Result LOINC	88734-9

Reflex Table for Amphiphysin Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505474	Amphiphysin Line Blot	505474	Amphiphysin Line Blot	94385-2
Reflex 1
Order Code	505474
Order Name	Amphiphysin Line Blot
Result Code	505474
Result Name	Amphiphysin Line Blot
UofM
Result LOINC	94385-2

Reflex Table for CRMP-5 IgG
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505487	CRMP-5 IgG Line Blot	505487	CRMP-5 IgG Line Blot	47401-5
Reflex 1
Order Code	505487
Order Name	CRMP-5 IgG Line Blot
Result Code	505487
Result Name	CRMP-5 IgG Line Blot
UofM
Result LOINC	47401-5

Reflex Table for AGNA-1
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505489	AGNA-1 Line Blot	505489	AGNA-1 Line Blot	82444-1
Reflex 1
Order Code	505489
Order Name	AGNA-1 Line Blot
Result Code	505489
Result Name	AGNA-1 Line Blot
UofM
Result LOINC	82444-1

Reflex Table for DPPX Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505281	DPPX Cell-based IFA	505281	DPPX Cell-based IFA	94676-4
Reflex 1
Order Code	505281
Order Name	DPPX Cell-based IFA
Result Code	505281
Result Name	DPPX Cell-based IFA
UofM
Result LOINC	94676-4

Reflex Table for mGluR1 Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505493	mGluR1 Cell-based IFA	505493	mGluR1 Cell-based IFA	93498-4
Reflex 1
Order Code	505493
Order Name	mGluR1 Cell-based IFA
Result Code	505493
Result Name	mGluR1 Cell-based IFA
UofM
Result LOINC	93498-4

Reflex Table for IgLON5 Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505498	IgLON5 Cell-based IFA	505498	IgLON5 Cell-based IFA	96478-3
Reflex 1
Order Code	505498
Order Name	IgLON5 Cell-based IFA
Result Code	505498
Result Name	IgLON5 Cell-based IFA
UofM
Result LOINC	96478-3

Reflex Table for Ma2/Ta Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505506	Ma2/Ta Line Blot	505506	Ma2/Ta Line Blot	82423-5
Reflex 1
Order Code	505506
Order Name	Ma2/Ta Line Blot
Result Code	505506
Result Name	Ma2/Ta Line Blot
UofM
Result LOINC	82423-5

Reflex Table for Zic4 Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505512	Zic4 Line Blot	505512	Zic4 Line Blot	101229-3
Reflex 1
Order Code	505512
Order Name	Zic4 Line Blot
Result Code	505512
Result Name	Zic4 Line Blot
UofM
Result LOINC	101229-3

Reflex Table for DNER Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505514	DNER Line Blot	505514	DNER Line Blot	82999-4
Reflex 1
Order Code	505514
Order Name	DNER Line Blot
Result Code	505514
Result Name	DNER Line Blot
UofM
Result LOINC	82999-4

Reflex Table for AMPA-R1 Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505521	AMPA-R-1 Cell-based IFA	505521	AMPA-R-1 Cell-based IFA	93869-6
Reflex 1
Order Code	505521
Order Name	AMPA-R-1 Cell-based IFA
Result Code	505521
Result Name	AMPA-R-1 Cell-based IFA
UofM
Result LOINC	93869-6

Reflex Table for AMPA-R2 Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505532	AMPA-R-2 Cell-based IFA	505532	AMPA-R-2 Cell-based IFA	93868-8
Reflex 1
Order Code	505532
Order Name	AMPA-R-2 Cell-based IFA
Result Code	505532
Result Name	AMPA-R-2 Cell-based IFA
UofM
Result LOINC	93868-8

Reflex Table for GABA-B-R Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505267	GABA-B Receptor Cell-based IFA	505267	GABA-B Receptor Cell-based IFA	93867-0
Reflex 1
Order Code	505267
Order Name	GABA-B Receptor Cell-based IFA
Result Code	505267
Result Name	GABA-B Receptor Cell-based IFA
UofM
Result LOINC	93867-0

Reflex Table for NMDA-R Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505376	NMDAR Antibody, Cell-based IFA	505376	NMDAR Antibody, Cell-based IFA	90839-2
Reflex 1
Order Code	505376
Order Name	NMDAR Antibody, Cell-based IFA
Result Code	505376
Result Name	NMDAR Antibody, Cell-based IFA
UofM
Result LOINC	90839-2

Reflex Table for GAD65 Antibody
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505546	GAD65 Line Blot	505546	GAD65 Line Blot	81725-4
Reflex 1
Order Code	505546
Order Name	GAD65 Line Blot
Result Code	505546
Result Name	GAD65 Line Blot
UofM
Result LOINC	81725-4

Reflex Table for CASPR2 Antibody,Cell-based IFA
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505432	Anti-CASPR2 Antibody Titer	505432	Anti-CASPR2 Antibody Titer	95600-3
Reflex 1
Order Code	505432
Order Name	Anti-CASPR2 Antibody Titer
Result Code	505432
Result Name	Anti-CASPR2 Antibody Titer
UofM
Result LOINC	95600-3

Reflex Table for LGI1 Antibody, Cell-based IFA
	Order Code	Order Name	Result Code	Result Name	Result LOINC
Reflex 1	505357	Anti-LGI1 Antibody Titer,Serum	505357	Anti-LGI1 Antibody Titer,Serum	90831-9
Reflex 1
Order Code	505357
Order Name	Anti-LGI1 Antibody Titer,Serum
Result Code	505357
Result Name	Anti-LGI1 Antibody Titer,Serum
UofM
Result LOINC	90831-9

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