GenoSure Archive®
GenoSure Archive® was designed to provide HIV-1 anti-retroviral (ARV) resistance data when a patient’s viral load is suppressed or too low for standard resistance testing. The assay interrogates the viral archive in peripheral blood mononuclear cells (PBMCs) using next-generation sequencing (NGS) to identify archived mutations and to then assign susceptibility calls of sensitive, resistant and resistance possible based on those mutations. Drug classes evaluated by GenoSure Archive® include nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), integrase inhibitors (INIs) and protease inhibitors (PIs).