Plasma Complete

TEST: 850450
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CPT: To be determined. Updates will be made when available.
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Synonyms

Labcorp Plasma Complete, Liquid Biopsy

Special Instructions

Specimens must be submitted using the Liquid Biopsy Specimen Kit and shipped directly to PGDx lab location using the shipping label provided in the kit.

Expected Turnaround Time

7 - 10 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements

Specimen

Blood

Volume

2 tubes of 10 mL each

Minimum Volume

2 tubes of 10 mL each

Container

Only the Liquid Biopsy Specimen Kit (PeopleSoft No. 137408) can be used for collection.

Collection

Collect 10 mL of whole blood into each of 2 Streck BCT tubes supplied in the Liquid Biopsy Specimen Kit.

Storage Instructions

Maintain at room temperature after collection and during shipping.

Stability Requirements

TemperaturePeriod
Room temperature7 days
Refrigerated0 days
Frozen0 days

Causes for Rejection

Samples not collected and submitted in Streck tubes; specimens submitted in expired or incorrect blood tubes; quantity not sufficient for analysis; specimens received more than seven days from collection; frozen specimens

Test Details

Use

The Labcorp Plasma Complete test is a next-generation sequencing based laboratory developed test for the detection of genomic sequence mutation in 521 clinically actionable or relevant genes including amplifications in 12 genes, translocations in 12 genes and microsatellite instability (MSI) from plasma-derived cell-free DNA (cfDNA). The test is intended to be used by qualified healthcare professional in accordance with professional oncology guidelines for patients already diagnosed with advanced stage or metastatic solid tumors. Test results are not prescriptive for the use of any specific therapeutic product.

Methodology

Next-generation sequencing

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf